Can plasma amyloid‐beta levels be considered as a potential biomarker to discriminate preclinical Alzheimer’s disease?

A case of acute rheumatic fever with new criteria, a disease that needs to be considered

Introduction: Acute rheumatic fever is an autoimmune disease that mainly affects the large joints. Early treatment of a throat infection following group A streptococcus prevents of acute rheumatic fever. Given the low prevalence of the disease, especially in a situation where there is excessive use of antibiotics in Iran, this study intends to report a patient with Acute rheumatic fever with mi...

Potential utility of soluble p3-alcadein α plasma levels as a biomarker for sporadic Alzheimer's disease.

Alcadeins (Alcs) constitute a family of neuronal type I membrane proteins (α, β, γ) that share identical localization and function to the amyloid-β protein precursor (AβPP) in the brain. Alcs are proteolyzed in neurons through successive cleavages via secretases, resulting in non-aggregative p3-Alc, where p3 corresponds to the AβPP-fragment. We found p3-Alcα detected in human plasma reflected t...

Can Male Fertility Be Improved Prior to Assisted Reproduction through The Control of Uncommonly Considered Factors?

Can hysterectomy be considered a risk factor for cardiovascular disease?

Context Hysterectomy is the most common nonobstetrical surgical procedure performed on women in the United States.2 In 2001, an estimated 649 000 hysterectomies were performed in the United States. Because most of the patients undergoing this procedure are between 25 and 54 years old, they live with the potential consequences of the procedure for many years.3 Thus, if hysterectomy is an indepen...

Can Prostate Specific Antigen Be Used as New Biomarker for Early Diagnosis of Breast Cancer?

Introduction: As a glycoprotein, Plasma Prostate-Specific Antigen (PSA) is mainly produced by prostate epithelial cells and is used as a major diagnostic tool for prostate cancer. A group of researchers relate the elevated number of estrogen receptors in breast cancer samples to the over-production of PSA in this type of cancer. Therefore, the present study aimed to determine the participants' ...